|TITLE||A novel aureothin diepoxide derivative from Streptomyces sp. NIIST-D31 strain|
|AUTHOR||Thankappan Drissya, D. K. Induja, M. S. Poornima, A. R. S. Jesmina, Bernard Prabha, Mathew Saumini,|
|JOURNAL||The Journal of Antibiotics|
A novel vicinal diepoxide of alloaureothin was isolated from Streptomyces sp. NIIST-D31 strain along with three carboxamides, p-aminobenzoic acid and 1,6-dimethoxyphenazine. Exhaustive 2D NMR analysis and analysis of experimental, theoretical CD spectra aided in establishing the structure of compound 1. Compound 1 inhibits adipogenesis and accumulation of lipid droplets during the differentiation of 3T3-L1 cells.
|KEYWORDS||Circular dichroism, Compound|