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TITLE A novel aureothin diepoxide derivative from Streptomyces sp. NIIST-D31 strain
AUTHOR Thankappan Drissya, D. K. Induja, M. S. Poornima, A. R. S. Jesmina, Bernard Prabha, Mathew Saumini,
YEAR 2022
JOURNAL The Journal of Antibiotics
ABSTRACT

A novel vicinal diepoxide of alloaureothin was isolated from Streptomyces sp. NIIST-D31 strain along with three carboxamides, p-aminobenzoic acid and 1,6-dimethoxyphenazine. Exhaustive 2D NMR analysis and analysis of experimental, theoretical CD spectra aided in establishing the structure of compound 1. Compound 1 inhibits adipogenesis and accumulation of lipid droplets during the differentiation of 3T3-L1 cells.

FULL ARTICLE https://www.nature.com/articles/s41429-022-00547-1#citeas
INSTRUMENT P-2000, J-810
KEYWORDS Circular dichroism, Compound
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