TS Science
The PR-4088 Prep SFC system is designed for large scale throughput with 21mm or 30mm columns to maximum sample purificaction. This system is versatile enough to be used for smaller scale prep using 10mm columns. Interchangeable modifier pumps can be configured to give highly accurate modifier compositions. JASCO SF-Nav provides complete integrated control for flow rate, temperature, sample injection and fractionation.
Preparative scale CO2 delivery of up to 150mL/min, or up to 200mL when combined with a modifier co-solvent.
Using columns from 10 to 30 mm ID, the PR-4088 Prep System can be used for separation and purification from 100mg to 100g per day of sample material.
PR-4088 Prep System is excellent for both Chiral and Achiral sample preparation.
Using SF-Nav software the PR-4088 Prep can be used with a wide variety of fraction collection methods, including time window, slope and/or threshold, to achieve high throughput stack injection.
SF-NAV controls your campaign; monitor the individual chromatograms, complete sets of stacked injections, pressure and temperature profiles throughout the system.
Several fraction collection regimes for use with larger sample bottles for larger scale purification.
PR-4088 uses the Patented DLI (Dual Line Injection) to ensure excellent chromatography when making large volume injections.
The PR-4088 fraction collection unit includes the patented dynamic back pressure regulator, 8 individual heated cyclone separators with a separate waste line. Fraction control allow sequential or stacked injection, with the option to collect the fractions between peaks to ensure there is no sample loss. Recoveries are typically in the region 95% or better with negligible cross contamination between fractions.
The PR-4088 SFC System can be used with a single detector or combination of detectors to control fractionation, including Mass Spec, UV-Vis, PDA and chiral (Circular Dichroism). And for applications requiring the utmost sensitivity, JASCO has designed the first high pressure flow cell designed for our fluorescence detectors making them compatible with SFC.