The semi-prep SFC has capacity for larger scale purification, but can still be used for analytical scale method development. The system is optimized for 10mm and 20mm ID columns. The open-bed fraction collector can be triggered on time, threshold or slope based on signals from up to 4 different detectors signals including UV, PDA, fluorescence, CD and/or MS. The macro cyclone separators provide simple gas-liquid separation for excellent fraction recoveries typically greater than 95%. Fractions can be collected using an open bed fraction collector or an 8-way valve.
Semi-Preparative Flow Rates
Using columns for 10 mm and 20mm ID, the semi-preparative SFC System can be used for separation and purification of 10 to 100 grams of sample material.
Typical Purification Range
Semi-preparative flow rates from 3mL/min to 50mL/min for purification of up to 100g of sample.
Wide Range of Detectors
Wide range of detectors including UV-Visible, PDA, Mass Spec, ELSD, FID and CD (circular dichroism for chiral applications). For applications that require the utmost sensitivity, JASCO has designed the first high pressure flow cell designed for the FP-4020 fluorescence detector making it compatible with SFC.
High-Throughput Fraction Collection System
Fraction collection with open bed fraction collector.
Dynamic Back Pressure Regulator
Patented dynamic back pressure regulator for accurate control of pressure for accurate and reproducible separations.
- Column Switching - Six or ten column switching for automatic selection.
- Solvent Switching - Six or ten modifier solvent selection.
- High-Capacity Column Oven - High capacity column oven for up to three 20mm columns.
- Powerful Software - ChromNav for simple control with powerful fractionation algorithms.