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Methane hydroxylation presents a promising approach to produce high-energy methanol from potent greenhouse gases, thereby contributing to a more sustainable future. Despite its environmental importance, current research on this process remains challenging due to the harsh operating conditions for the activation of inert C-H bond in methane. In nature, methane mon...
Continue readingThe biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) involves binding of the N-terminal leader region of precursor peptides to peptide-modifying enzymes and subsequent modification of the C-terminal core. Canonical RiPP leaders are short and unstructured. However, atypical RiPP leaders called nitrile hydratase-like leader...
Continue readingComputational protein and peptide design is emerging as a transformative framework for engineering macromolecules with precise structures and functions, offering innovative solutions in medicine, biotechnology and materials science. However, current methods predominantly rely on generative models, which are expensive to train and modify. Here, we introduce the Ke...
Continue readingThe existence of linear cholesterol-recognition motifs in transmembrane domains has long been debated. Evolutionary molecular dynamics (Evo-MD) simulations—genetic algorithms guided by (coarse-grained) molecular force-fields–reveal that thermodynamic optimal cholesterol attraction in isolated alpha-helical transmembrane domains occurs when multiple co...
Continue readingThis work presents the synthesis of Sn doped NiO nanostructures with varying doping concentrations (0 %, 1.25 %, 2.5 %, 5 %, and 10 %) using a hydrothermal method, aiming to explore the impact of Sn incorporation on their structural, optical, and photoelectrical behavior. X-ray diffraction (XRD) patterns confirmed the retention of the face-centered cubic phase acro...
Continue readingThe enzymatic depolymerization of single-use plastic products, primarily made from poly(ethylene terephthalate) (PET), is now a reality. Herein, we report the development of an innovative tandem system process that uses engineered enzymes and Escherichia coli strains to depolymerize PET and convert the resulting products into enantiomers of alanine, useful amino ac...
Continue readingChiral recognition through fluorescence changes enables the rapid and sensitive determination of enantiomers. However, the rational design and synthesis of fluorescent probes for efficient chiral recognition remain a challenge. Here we present a novel platform for chiral recognition based on zero-dimensional hybrid copper halides with unique symmetry-dependent pr...
Continue readingThe all-inorganic lead halide perovskites, including cesium lead iodide (CsPbI3), have attracted significant attention due to their possible applications in photo voltaics, light-emitting devices, and other optoelectronic technologies, driven by their intrinsic optoelectronic properties. This study introduces a simple, green, and scalable solution synthesis method ...
Continue readingA vision system with efficient infrared-sensitive optical synapses is crucial for enabling infrared radiation detection and target recognition for some predators hunting in the dark. Current 2D synaptic devices typically adopt the strategy of charge trap and release to achieve intelligent sensing and visual recognition. However, the response wavelength is limited i...
Continue readingThere has been considerable progress in colloidal quantum dot light-emitting diodes (QD-LEDs) for display applications. However, their commercialization remains challenging, because of the difficulty in achieving high-resolution, full-color patterning of quantum dots (QDs) without degrading their optical properties. Direct photolithography has attracted attention, ...
Continue readingDengue and leptospirosis are prevalent diseases in tropical and subtropical regions, posing significant public health challenges. These illnesses exhibit overlapping symptoms, including fever, muscle pain, and headaches, which complicates diagnosis and delays appropriate treatment. This study explores the use of attenuated total reflectance-Fourier transform infr...
Continue readingSpectral decoupling concerns about selective modulation of specific regions over the wide electromagnetic spectrum, which is highly desirable for smart handling of light/heat, such as photo-thermal regulation, multiband camouflage, etc. However, effective spectral decoupling is still lacking, especially for independent control over non-adjacent bands with orders ...
Continue readingThis study successfully synthesized Hydrochar (HC) and Modified Hydrochar (MHC), two affordable and environmentally friendly adsorbents, utilizing an integration of chemical activation and hydrothermal carbonization. Subsequently, the artificially produced adsorbents were employed to eradicate the Alizarin Red S (ARS) dye from the aquatic environment. The physica...
Continue readingWith the goal of creating environmentally friendly therapeutic Carbon Quantum Dots (CQD), we explored the potential of a wildflower, Mahua (Madhuca longifolia), as a carbon source. The Mahua tree holds significant socio-economic importance in eastern and central India. Applying a conventional hydrothermal technique, we synthesized CQDs of a tiny size of ~ ...
Continue readingThis study presents the synthesis, comprehensive characterization, and application of zinc tin oxide/polyvinyl alcohol (ZTO/PVA) nanocomposites as sensitive platforms for arsenic detection using quartz crystal microbalance (QCM) sensors. ZTO nanoparticles were synthesized via an optimized hydrothermal method and incorporated into PVA matrices at 5, 8, and 10 wt%....
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