TS Science
Applications
Application
| TITLE | Novel inducible nitric oxide synthase-inhibiting cytochalasins from an oyster-derived fungus Westerdykella dispersa Ca4-13: structural insights and molecular docking analysis |
|---|---|
| AUTHOR | Shu-Jung Huang, Su-Jung Hsu, Shih-Wei Wang, Yi-Chien Liu, Cheng-Yan Jiang, George Hsiao & Tzong-Huei Lee |
| YEAR | 2025 |
| JOURNAL | Botanical Studies |
| ABSTRACT | Marine-derived microorganisms are renowned for producing structurally diverse secondary metabolites with notable biological activities, serving as a promising reservoir for pharmaceutical development. In this study, the fungal strain Westerdykella dispersa Ca4-13, isolated from the edible oyster Crassostrea angulata, was investigated for its potential anti-inflammatory and cytoprotective properties using BV-2 microglial cells as a model system. |
| FULL ARTICLE | https://link.springer.com/article/10.1186/s40529-025-00481-z |
| INSTRUMENT | P-2000, FTIR-4100 |
| KEYWORDS | Bacterial toxins, Fungal biology, Natural Products, Neurospora crassa, Saccharomyces cerevisiae, Thioredoxins |
약관
약관내용